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Prospective Exploratory Study on rTMS for Migraine Under the Guidance of MEG

RecruitingNAAges 15 Years - 50 YearsAllRuijin Hospital
NCT06796725 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Using magnetoencephalography to locate and regulate targets in migraine patients, repeating transcranial magnetic stimulation to physically regulate targets, and evaluating the safety and effectiveness of this treatment method through headache related scales. Using whole genome data and scale scores for correlation analysis, and conducting randomized controls with traditional drugs to explore new approaches for migraine.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Complies with specific disease diagnosis: A. Headaches that meet the criteria of B and C (headaches that meet the characteristics of tension headaches or migraines) should occur at least 15 days per month and last for at least 3 months; B. Headaches that meet the criteria of 1.1 migraine without aura diagnosis B-D or 1.2 migraine with aura B and C occurring at least 5 times; C. Headache meets any of the following criteria and occurs for more than 8 days per month, lasting for more than 3 months: ①1.1 C and D of migraine without aura②1.2 B and C of migraine with aura③ The migraine attack perceived by the patient can be relieved by taking triptan or ergot, which cannot be better explained by other diagnoses in ICHD-3. * Must be able to swallow tablets * Signed and dated informed consent form Promise to comply with research procedures and cooperate in implementing the entire research process Exclusion Criteria: * Age under 15 years old; Accompanied by optic disc edema, focal symptoms and signs of the nervous system (except for typical visual and sensory precursors) or cognitive impairment; Sudden and rapidly peaking severe headaches (thunderous headaches) * Accompanied by fever; New onset headaches in adults, especially after the age of 50; Headaches in patients with high coagulation risk * New headache in patients with tumor or AIDS history; Headaches related to changes in body position; * History of epileptic seizures
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What it tests

  • rTMS
  • Sibelium
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Where

1 site
Ruijin Hospital
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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