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Urethral PeRfusion Index-Guided Hemodynamic ManagemenT in Patients Having Major Abdominal Surgery: the UPRIGHT Randomized Feasibility Trial

RecruitingNAAges 45 Years - anyAllUniversitätsklinikum Hamburg-Eppendorf
NCT06799832 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

We will perform this single-center pilot trial to determine if the intraoperative urethral perfusion index is higher in patients assigned to maintaining postinduction baseline urethral perfusion index than in patients assigned to routine care (with blinded urethral perfusion index monitoring). As pre-planned substudies, we will also assess the agreement between a) urethral perfusion index-derived pulse rate and heart rate measured with an electrocardiogram and b) between the urethral perfusion index and the peripheral perfusion index.

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📋 Eligibility rules (as published)
Inclusion Criteria: * at least 45 years old * scheduled for elective major abdominal surgery (involving visceral organs with an expected duration of at least 120 minutes) * indication for an arterial catheter * indication for an urinary catheter Exclusion Criteria: * Pregnancy * Planned surgery: nephrectomy, liver or kidney transplantation surgery * Patients who previously had surgery on the urethra or bladder * Patients without clinical indication for continuous blood pressure monitoring with an intraarterial catheter
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What it tests

  • urethal perfusion index monitoring
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Where

2 sites
University Medical Center Hamburg-Eppendorf
Hamburg, Germany
University Medical Center Hamburg-Eppendorf
Hamburg, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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