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Lung Recruitment During Chest Physiotherapy in Mechanically Ventilated Patients

RecruitingNAAges 18 Years - 100 YearsAllAssistance Publique - Hôpitaux de Paris
NCT06805357 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In intensive care, respiratory physiotherapy is an integral part of the daily care of patients under invasive mechanical ventilation. Its goals are to improve the clearance of bronchial secretions to allow for the resolution of atelectasis and alveolar recruitment, thereby enhancing respiratory mechanics and gas exchange. The most widespread technique in France is external expiratory compression of the chest. The effectiveness of this technique depends on the selection of patients (it seems to be more effective in patients with higher secretion levels) and on the practical implementation of the technique (favoring brief and vigorous compressions at the beginning of expiration). However, the effect of the artificial ventilator settings, particularly the ventilatory mode used during the respiratory physiotherapy session, has never been evaluated. The two most commonly used ventilatory mod

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient under assisted ventilation (in V-ACV or PSV) triggering all ventilator cycles * Patient deemed " secretive ": requiring ≥ 2 tracheal aspirations every 3 hours * Patient (or relative) who has given consent to participate in the research * Patient covered by social security Exclusion Criteria: * Age under 18 years * Legal guardian required * Recent cardiac and/or thoracic and/or abdominal surgery (\< 3 months) * Rib fracture(s) * Pneumothorax and/or presence of a chest drain * Recent neurosurgery (\< 3 months) and/or proven or suspected increased intracranial pressure (ICP) * Hemodynamic instability defined as: noradrenaline ≥ 1mg/h, adrenaline ≥ 0.5 mg/h, dobutamine ≥ 5γ/kg/min. * Respiratory instability defined as: PEEP \> 10 cmH2O and/or PaO2/FiO2 \< 150 mm Hg * Pregnancy * Hemoptysis * Sever skin lesions (e.g., burns, Lyell's syndrome) * Patient under foreign health insurance
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What it tests

  • Chest Physiotherapy by Rib Cage Compressions (RCC)
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Where

1 site
Intensive Care Medicine Department Henri Mondor Hospital
Créteil, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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