CLAiR Pivotal Study

Inclusion Criteria: 1. Male or female, aged 40-75 years 2. Participants must be capable of providing informed consent, demonstrating understanding of the study details, and willingly sign a consent form or verbally confirm their consent in the presence of a witness. 3. Stated willingness to comply with all study procedures and availability for the duration of the study Exclusion Criteria: An individual who meets any of the following criteria will be excluded from participation in this study: 1. Known history of atherosclerotic cardiovascular disease, including stroke, heart attack, coronary artery surgery, or stenting 2. Current use of cholesterol-lowering medication, such as a statin 3. Pregnancy 4. A person who has (in at least one eye): * Persistent vision impairment: legally blind when wearing current driving glasses or known VA\<20/400 * Known pathological myopia * Previous treatment or currently under the care for a retinal disease by a specialist (e.g., ophthalmologist)