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Intravenous Versus Perineural Ondansetron for Laparoscopic Sleeve Gastrectomy

RecruitingNAAges 18 Years - 65 YearsAllTanta University
NCT06810882 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective randomized non-inferiority study will be conducted to compare the analgesic anti-emetic effects of intravenous ondansetron versus perineural ondansetron in patients undergoing laparoscopic sleeve gastrectomy.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients of either sex * American Society Anesthesiologists physical (ASA) status II-III * age between 18-65 years old * Body mass index (BMI) \>35 kg/m2 with comorbidity or \> 40 kg/m2 -- undergoing laparoscopic sleeve gastrectomy with intraoperative surgeon performed laparoscopic paragastric autonomic neural blockade.. Exclusion Criteria: * Allergy to experimental drugs. * Known to have long QT, previous history of postoperative nausea and vomiting * Abuse of alcohol, analgesia, or sedative antidepressant drugs * Chronic pain disorders * History of previous upper gastrointestinal system surgery, those with surgery-related complications during or after surgery. * Liver or kidney failure * Performance of concomitant procedures in addition to laparoscopic sleeve gastrectomy * Anesthetic complications that may alter the postoperative management protocol.
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What it tests

  • Perineural ondansetron
  • Intravenous ondansetron
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Where

1 site
Tanta University Hospitals
Tanta, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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