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Surviving the Pediatric Intensive Care Unit (PICU)

Recruitingn/aAges 28 Days - 16 YearsAllKK Women's and Children's Hospital
NCT06812130 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Improvement in pediatric intensive care unit (PICU) supportive care has led to improvement in clinical outcomes and decreased mortality in pediatric critical illness. However, PICU survivors are at risk of long-term health sequalae. Given the increased recognition of physical, cognitive, and psychological sequelae in PICU survivors, the concept of post-intensive care syndrome-pediatrics (PICS-p) has been proposed. Besides the PICU patient/survivor, the PICS-p framework also highlights the impacts of a child's critical illness has on the family. The impact of a PICU admission extends beyond the patient and parents, potentially affecting healthy siblings who are navigating their own developmental challenges. Healthy siblings may face emotional distress, increased responsibilities, and disruptions in their daily routines, all of which can contribute to long-term negative outcomes if unaddre

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📋 Eligibility rules (as published)
Inclusion Criteria: \[HOPE Cohort\] 1. Between 28 days - 16 years of age at PICU admission 2. Have an expected PICU stay \> 48 hours\* \[SHACK-S Cohort\] 1. Healthy children (aged 4 -16 years old) with critically ill sibling between 28 days - 16 years of age at PICU admission 2. Has a critically ill sibling who has an expected PICU stay \> 48 hours 3. Lives in the same household as the critically ill sibling and parents prior to admission Exclusion Criteria: \[HOPE Cohort\] 1. Do-Not-Resuscitate status 2. Lack of informed consent 3. Prior enrolment in this study \[SHACK-S Cohort\] 1. Children of critically ill sibling with Do-Not-Resuscitate status 2. Children with condition listed on paediatric Complex Chronic Conditions (CCC) system Version 3.0 or with neurocognitive/neurodevelopmental delays or disorders 3. Previous admission to PICU 4. Lack of informed consent 5. Prior enrolment in this study * Note: For participating study sites without a dedicated PICU (e.g., sites where patients are managed in a combined ward under High Dependency (HD) or ICU status), PICU stay will be defined as the duration during which the patient is assigned an ICU status. The determination of ICU status will be made at the discretion of the respective site's study team and Site-PI.
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What it tests

  • This is a non-interventional study.
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Where

2 sites
National University Singapore
Singapore, Singapore
KK Women's and Children's Hospital
Singapore, Singapore
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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