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IVUS Guided PCI in Patients With Chronic Kidney Disease

RecruitingNAAges 18 Years - anyAllAssistance Publique - Hôpitaux de Paris
NCT06813534 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The incidence of contrast-induced nephropathy (CIN) is high (\> 25%) in patients with severe chronic renal disease (CKD) who undergo a percutaneous coronary procedure. The development of CIN is a factor of poor prognosis and is associated with the occurrence of irreversible CKD, the need for dialysis, increased length of stay and hospital costs as well as the risk of death. There is no specific treatment for N-PCI, so its prevention is essential. Although many studies have been conducted to identify, compare and implement different pharmacological strategies for the prevention of CIN before percutaneous coronary procedurse, few per-procedural strategies have been studied to prevent this risk. Intracoronary ultrasound (IVUS) is an essential tool, used routinely to guide percutaneous coronary procedures thanks to ultrasound, it does not require the injection of iodine contrast. The main

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients over 18 years old * Indication for PCI * Chronic kidney disease with creatinine clearance ≤ 30 mL/min/1.73m² * Feasibility of IVUS determined by 2 trained interventional cardiologist * Affiliated to social security Exclusion Criteria: * Iodine contrast injection in the previous 72 hours * Known allergy to iodine contrast * Permanent dialysis * Chronic total occlusion * Hemodynamic instability * Legal protection * Pregnant of breastfeeding patients * Patients on "AME"
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What it tests

  • Intravascular Ultrasound guided PCI
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Where

2 sites
Romain GALLET
Créteil, France
Romain GALLET
Créteil, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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