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A Novel Ureteric Stent in Kidney Stone Patients and Oncology Patients Compared to a Conventional JJ Stent

RecruitingNAAges 18 Years - 99 YearsAllUniversity of Southampton
NCT06815120 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Urological stents and catheters often lead to inflammation, causing pain and infection in the urinary tract. Moreover, 80% of stents are associated with pain, negatively impacting on QoL and mental health. Offering novel designs with significantly lower E\&B leads to a reduction in UTIs and improves QoL. Reducing hospital admissions (from 3 to 1 per patient, annually) would free \>100,000 bed-nights, allowing the elderly to regain independence. Our proposed research could have a significant impact towards fulfilling the 'healthy-ageing' Grand Challenge. Additionally, the novel stent reduces prevalence of infections and therefore, of antibiotic prescriptions contributing to the Global AMR challenge.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Aged 18 years or over 2. Ureteric stents clinically indicated either due to kidney stones or abdominal/pelvic cancers compressing ureters 3. Previous experience with ureteric stents 4. Awaiting insersion/replacement of stents 5. Ability to give consent 6. Ability to interact with study documentation 7. Sufficient English to complete study documentations and questionnaires Exclusion Criteria: 1. Expected survival \<4months 2. Unfit for stent insertion 3. Unable to comply with study processes Pregnancy
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What it tests

  • Experimental ureteric stent with specially shaped side-holes that prevent stagnation points (i.e., areas of low flow that cause particles to settle and E&B)
  • Qualitative interview
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Where

2 sites
University Hospital Southampton
Southampton, United Kingdom
University College Hospital London
London, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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