🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD

RecruitingNAAges 50 Years - 80 YearsAllOregon Health and Science University
NCT06815302 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkinson's disease, as assessed by patients, clinicians, and wearable sensors, and 2) to explore whether two different rehabilitation intervention can reduce FOG and improve daily life mobility in people with FOG sufficiently to justify a clinical trial. Participants will: * Be randomly assigned to one of two intervention groups (turning-focused agility exercise or strength-based exercise) * Have one-on-one training sessions three times per week for 6 weeks * Perform in-lab assessments before beginning and after completing the study intervention * Use wearable mobility sensors during daily life to measure their walking and balance

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * diagnosis of idiopathic PD from movement disorders neurologist with the United Kingdom Brain Bank criteria of bradykinesia with one or more of the following - rest tremor, rigidity, and balance problems not from visual, vestibular, cerebellar or proprioceptive conditions * reporting FOG in the New Freezing of Gait questionnaire (N-FOGQ) * Hoehn \& Yahr stages II-IV * ages 50-80 years old * cognitive ability sufficient to participate in testing procedures and exercise classes * be willing and able to participate in exercise intervention 3x/week for 6 weeks Exclusion Criteria: * Major musculoskeletal or neurological disorders, structural brain disease, epilepsy, acute illness or health history, other than PD, significantly affecting gait and turning (i.e., musculoskeletal disorder, vestibular problem, head injury, stroke, cardiac disease) * medical condition or medications that precludes moderate-intensity exercise * Montreal Cognitive Assessment (MoCA) ≤21 or inability to follow directions * excessive use of alcohol or recreational drugs * recent change in medication * inability to stand and walk for 2 minutes without an assistive device
💊

What it tests

  • Experimental intervention
  • Active intervention
📍

Where

3 sites
Arizona State University
Tempe, United States
Oregon Health and Science University
Portland, United States
University of São Paulo, Bauru Campus
Bauru, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy