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Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults

RecruitingEARLY Phase 1Ages 21 Years - anyAllRoswell Park Cancer Institute
NCT06816459 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This clinical trial tests how well current daily smoking adults can identify flavors of cigarettes. Menthol cigarettes account for 31 percent of cigarettes sold in the United States. Flavors such as menthol play an important role in the start and continued use of tobacco products. Two ways users experience flavor is through smell and taste. Menthol has cooling and numbing properties that can increase perceptions of smoothness and reduce the perceived harshness of smoke. Menthol adds a taste and aroma commonly described as "minty". The effect of menthol flavoring on smoking behavior has been studied. Use of menthol cigarettes has been associated with greater nicotine dependence and is associated with both fewer quit attempts and lower odds of quit success. In 2022, the Food and Drug Administration proposed to restrict the use of menthol as a flavor in cigarettes. Menthol has already been

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📋 Eligibility rules (as published)
Inclusion Criteria: * Aged 21 years or older * Current daily smoker of factory-made menthol cigarettes * General good health (assessed by self-rated health item) * Completion of Brief Smell Identification Test (B-SIT) with no identification of deficits Exclusion Criteria: * Daily concurrent use of other tobacco products (e.g., e-cigarettes, cigars, smokeless tobacco) * Known allergies to mint (peppermint, spearmint), menthol * Self-reported olfactory or taste deficits * Pregnant or nursing participants, as indicated by self-report * History of medications known to interfere with sense of smell * Positive diagnosis of coronavirus 2019 (COVID-19) within 10 days of enrollment * Current upper respiratory infection or sinus congestion (e.g., cold, flu, seasonal allergies) (by self report)
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What it tests

  • Cigarette smell test
  • Cigarette Taste Test
  • Study questionnaires
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Where

1 site
Roswell Park Cancer Institute
Buffalo, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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