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Effect of Chitin and Ascorbic Acid on Dietary Insect Iron Absorption

RecruitingNAAges 18 Years - 45 YearsFemaleSwiss Distance University of Applied Sciences
NCT06822062 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Iron is involved in many vital metabolic processes such as oxygen transport, electron transport in cells, DNA synthesis and repair, and muscle metabolism. However, iron deficiency and iron deficiency anemia continue to affect many people, particularly preschool children (\<5 years), adolescents, and pregnant and non-pregnant women of childbearing age. Iron deficiency is characterized by a lack of total iron stores in the body, which is mainly caused by insufficient dietary iron intake, physiologically increased iron requirements, poor intestinal iron absorption, or chronic blood loss. Animal foods are important sources of highly bioavailable iron in the human diet. Meeting human nutritional needs for the rapidly increasing world population while targeting food production within the planetary boundaries will require the identification of sustainable iron sources, such as edible insects. A

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female aged between 18-45 years * Normal BMI (18.5 - 24.9 kg/m2) * Body weight \< 70 kg * Low iron status (being in the lower half of the serum ferritin distribution at screening) Exclusion Criteria: * Anaemia (Hb \< 12 g/dL) * Inflammation (CRP \> 5.0 mg/L) * Pregnancy or intention to become pregnant during the study or within 30 days after the discontinuation of the study intervention * Lactating up to 6 weeks before the study initiation * Chronic digestive, renal and/or metabolic diseases * Antibiotics in the last 4 weeks prior to the study and during the study * Mineral and vitamin supplementation in the last 2 weeks prior to the study and during the course of the study * Chronic medication intake (except for oral contraceptives) * Blood transfusion, blood donation or significant blood loss (accident, surgery) over the past 4 months * Earlier participation in a study using stable isotopes or in any clinical study within the last 30 days * Food allergies, especially known hypersensitivity to crustacea, dust mites, sea food, gluten, milk, or eggs * Cigarette smoking (\> 1 cigarette per day)
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What it tests

  • Meal A
  • Meal B
  • Meal C
  • Meal D
  • Meal E
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Where

1 site
ETH Zürich
Zurich, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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