🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars

RecruitingNAAges 6 Years - 12 YearsAllAlexandria University
NCT06826456 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Background: Subjecting human dental enamel to sub-ablative laser has been suggested as a novel way of caries prevention. However, further studies are needed to establish its use as a routine clinical procedure for caries prevention. The aim of this study: This study aims to evaluate the effect of Er,Cr:YSGG subablative laser irradiation on caries resistance of occlusal fissures of permanent molars. Materials and methods: In-vivo study, a split mouth randomized controlled trial with sixty patients having two fully erupted bilateral first permanent molars (ICDAS-II score 0,1 or 2). The pits and fissures will be subjected to sub-ablative power of Er,Cr:YSGG Laser (Group 1, n=90) and will be compared with fluoride varnish application on the first permanent molars in the same arch(Group 2,n=90). DIAGNOdentTM readings and changes in ICDAS-II score will be assessed at base line and at 3,6,9 a

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Participants of age 6-12 years old * Patients ranking definitely positive or positive on Frankl behavior rating scale * Having at least two bilateral fully erupted first permanent molars with untreated non-cavitated occlusal surfaces with deep grooves, the included teeth will have International Detection and Assessment System (ICDAS-II)/ severity scores 0, 1 or 2 * Initial DIAGNOdent Score not exceeding value of 25 indicating only enamel involvement * Patients whom their parents are willing to comply with all study procedures and protocols and will be given an informed consent to participate Exclusion Criteria: * Patients with any known medical history of systemic diseases * Patients having first permanent molar with hypoplastic or hypocalcified enamel * Patients using medications that may affect the oral flora or salivary flow * Patients treated with in-office fluoride treatment within the last 3 months prior to being enrolled in the study. * Patients showing evidence of poor oral hygiene according to Silness and Löe plaque index
💊

What it tests

  • sub-ablative Er,Cr:YSGG laser
  • Fluoride varnish application
📍

Where

1 site
Alexandria University
Alexandria, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy