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Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program (LIFE-SCREEN)

RecruitingNAAges 35 Years - 74 YearsAllCentre Leon Berard
NCT06827366 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The investigators propose a randomized controlled trial to develop and evaluate the impact of promoting advice on diet and lifestyle recommendations for cancer prevention at colorectal cancer screening among individuals who may be at higher risk for colorectal cancer (CRC). The specific objectives of this study are to 1) develop a lifestyle intervention based on evidenced-based diet and lifestyle recommendations (i.e. those proposed by the World Cancer Research Fund (WCRF) and the French National Cancer Institute); 2) evaluate the effect of the intervention on the adherence to the target diet and lifestyle recommendations as well as other subjective health measures, including quality of life; 3) evaluate the effect of the intervention on anthropometrics.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Having read the information note and agreeing to participate * Will and availability to be committed for a full year * At high risk for CRC but CRC negative * Affiliated to a health security system * Having a score on the adherence to the recommendation lower than or equal to 7 out of 9 at baseline. * Able to read, write and understand French Exclusion Criteria: * Under a strict diet such as meal replacements, diets for co-morbidities such as diabetes * Immobile due to physical constraints (e.g. handicap that is not compatible with physical activities) * Extensive intestinal surgery such as colectomy or surgical resection of the colon * Chronic gastrointestinal illness (IBD, IBS, celiac disease) * Colorectal cancer confirmed or history of a primary cancer * Severe malnutrition * Pregnant * Participation in another lifestyle study NB : For this study, there is no exclusion period from other research, and participants can simultaneously take part in another study unless it concerns lifestyle.
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What it tests

  • Diet and lifestyle advice following a positive FIT test and diagnostic colonoscopy
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Where

1 site
Centre Léon Bérard
Lyon, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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