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A Study of SHR-A1811 in Subjects With Ovarian Cancer

RecruitingPhase 3Ages 18 Years - 75 YearsFemaleJiangsu HengRui Medicine Co., Ltd.
NCT06828354 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is an open-label study to evaluate the safety and efficacy of SHR-A1811 for injection in subjects with ovarian cancer.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. The subjects voluntarily joined the study and signed the Informed consent forms (ICF). 2. Measurable disease, as defined by RECIST v1.1. 3. The Eastern Cancer Cooperative Group (ECOG) performance status of 0 or 1. 4. Life expectancy ≥ 12 weeks. Exclusion Criteria: 1. Symptomatic, untreated or active central nervous system metastases. 2. Have uncontrolled or severe cardiovascular disease. 3. With any active autoimmune disease or history of autoimmune disease. 4. Patients with active hepatitis B or hepatitis C. 5. Severe infections prior to initiation of study treatment. 6. Patients with active tuberculosis.
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What it tests

  • SHR-A1811
  • Paclitaxel Injection
  • Doxorubicin Hydrochloride Liposome Injection
  • Gemcitabine Hydrochloride for Injection
  • Topotecan Hydrochloride for Injection
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Where

2 sites
Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology
Wuhan, China
Qilu Hospital of Shandong University
Jinan, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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