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Using AI Systems to Optimize the Clinical Outcome of Stroke Patients

RecruitingNAAges 65 Years - 80 YearsAllChinese University of Hong Kong
NCT06828679 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This project addresses the imminent challenge of providing adequate motor rehabilitation to a growing number of stroke survivors amidst the ageing population, decreasing age of stroke, and shortage of physical/occupational therapists in Hong Kong through AI and precision rehabilitation. To reduce the socioeconomic burden from the stroke survivors' loss of independence and their care (\>HK$15 billion/year), the efficacy of rehabilitation and efficiency of its delivery must be improved. These goals can be achieved by prescribing them with individually tailored rehabilitations predicted to yield maximal functional return. Defining a predictive model for such personalization remains challenging given the immense heterogeneity of stroke. The investigators aim to build an explainable AI system that predicts a subject's recovery potential and the treatment option that may realize this potential

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📋 Eligibility rules (as published)
IInclusion Criteria: * Age 65-80 * 1-6 months after onset of a first-time unilateral stroke rostral to midbrain * Moderate-to-severe motor impairment of one upper limb (Fugl-Meyer Assessment for Upper Extremity of 10-50 out of 66); * Able to provide written informed consent; * Detectable electromyographic (EMG) activities in flexor digitorum-flexor carpi radialis and extensor digitorum-extensor carpi ulnaris muscle groups, with EMG from each muscle group exceeding 3 standard deviations above baseline mean. This last criterion is essential for successful NMES training Exclusion Criteria: * Unconscious or bed-bound; * Uncontrollable diabetes; * Anticipated non-adherence to treatment schedule; * On cardiac pacemaker; * Other severe comorbidities (heart/kidney failure, deranged liver function).
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What it tests

  • Acupuncture
  • control group
  • Robotic Training
  • Neuromuscular Electrical Stimulation Group
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Where

1 site
The Chinese University of Hong Kong
Hong Kong, Hong Kong
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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