AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Peri-implantitis Treatment With Chitosan Brush

RecruitingNAAges 18 Years - 65 YearsAllHacettepe University
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

In dentistry, dental implant applications for tooth loss/deficiency are prominent and provide successful long-term results in terms of functionality and aesthetics. However, peri-implant diseases such as peri-implant mucositis and peri-implantitis may develop due to biofilm accumulation around the implant. In peri-implantitis, in addition to the clinical inflammation findings seen in peri-implant mucositis, there is also progressive bone loss. This condition is to be treated with non-surgical or surgical methods. Titanium curettes, ultrasonic instruments, laser systems, and chitosan brushes are used for biofilm removal in non-surgical treatment. Chitosan is a natural polysaccharide obtained from chitin. It is biocompatible, biodegradable, and has antibacterial activity. In addition, chitosan reduces the levels of IL-1ฮฒ, IL-6, and TNF-ฮฑ, which also play a role in the pathogenesis of peri-

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Presence of peri-implantitis in an implant that has been in function for more than 12 months * Age โ‰ฅ 18 and \< 65 * Agreeing to participate in the study after reading the informed consent form * Completion of periodontal treatment of patients diagnosed with periodontitis before inclusion in the study Exclusion Criteria: * Patients under 18 years of age * Patients who have received or are currently receiving radiotherapy, chemotherapy and long-term systemic corticosteroid treatment * Patients who received systemic antibiotics within 6 months from baseline * Pregnant or lactating patients * Patients with anatomical abnormalities around the implant (e.g., apically positioned implants adjacent to a tooth) * Patients with prostheses that prevent access for implant debridement with chitosan brushes or titanium curettes * Implants with an overdenture superstructure * Implants to be explanted * Patients with ASA score โ‰ฅ 3 * Patients reporting reactions or adverse events to chitosan, stainless steel, adhesives, or polypropylene * Clinically mobile implants * Recently placed and non-osseointegrated implants * Around major nerves and blood vessels, if there is a risk of structural damage
๐Ÿ’Š

What it tests

  • Non-surgical periodontal treatment with chitosan brush
  • Non-surgical treatment of pre-implantitis with titanium curette
๐Ÿ“

Where

1 site
Hacettepe University
Ankara, Turkey (Tรผrkiye)
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy