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A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

RecruitingPhase 2Ages 18 Years - 68 YearsAllMaze Therapeutics
NCT06830629 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease.

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📋 Eligibility rules (as published)
Key Inclusion Criteria: * APOL1 high risk genotype of G1/G1, G2/G2, or G1/G2 * Chronic kidney disease with persistent albuminuria Key Exclusion Criteria: * Organ or bone marrow transplantation * History of active cancer within past 2 years, except for treated non-melanoma skin cancer, stage 0 cervical cancer, or stage 1 prostate cancer * Conditions that may alter drug absorption, e.g., history of bariatric surgery * Type I diabetes * Pregnant or currently nursing Other inclusion/exclusion criteria defined in protocol apply.
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What it tests

  • MZE829
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Where

79 sites
Research Site
Decatur, United States
Research Site
Huntsville, United States
Research Site
Montgomery, United States
Research Site
Montgomery, United States
Research Site
Bloomfield, United States
Research Site
Washington D.C., United States
Research Site
Atlantis, United States
Research Site
Brandon, United States

…and 71 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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