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The ROAR Study: Reactive Oxygen Species and Reproduction

Recruitingn/aAges 18 Years - 43 YearsAllUniversity of California, San Francisco
NCT06831019 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a prospective cohort study characterizing follicular fluid and serum levels of oxidative stress in women with various infertility diagnoses undergoing in vitro fertilization, and assessing the relationship of oxidative stress to oocyte competence as determined by embryo development outcomes. Furthermore, we will measure oxidative stress in sperm and correlate the overall oxidative stress within the couple with IVF and pregnancy outcomes of the resultant embryos.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Female age 18-43 years 2. Subjects planning blastocyst culture for preimplantation genetic screening (PGS) for aneuploidy. 3. Male partners 18 years of age or older. 4. Must be a registered patient at UCSF Center for Reproductive Health 5. Patient and partner must both be physically present on the day of retreival Exclusion Criteria: 1. Female partner age 44 or older 2. Planning fresh transfer (hybrid PGS cycle) 3. Cleavage stage biopsy 4. Planning to use frozen sperm
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What it tests

  • Oxidative stress markers
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Where

1 site
University of California, San Francisco
San Francisco, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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