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Lifestyle Intervention in the Memory Clinics of General and Academic Hospitals Trial

RecruitingNAAges 50 Years - anyAllMaastricht University Medical Center
NCT06832761 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Lifestyle Intervention in the memory clinics of General and academic Hospitals Trial (LIGHT) is a multi-center, randomized, controlled, lifestyle intervention trial among 300 older adults (≥50 years) with subjective cognitive decline (SCD) and mild cognitive impairment (MCI) at risk of dementia. Participants are randomized in a 1:1 ratio to Group A (tailored lifestyle intervention) or Group B (general health advice) for a duration of 12 months. The lifestyle intervention comprises three parts 1) Lifestyle coaching, 2) a voucher program, and 3) online self-management. Group B will receive general health advice.

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📋 Eligibility rules (as published)
Inclusion Criteria: * ≥50 years of age at pre-screening; * Having a diagnosis of SCD or MCI; * Presence of ≥ 2 modifiable risk factors for dementia. Exclusion Criteria: * Having a diagnosis of dementia; * Insufficient understanding of the Dutch language; * Conditions affecting safe and continuous engagement in the intervention (e.g. under treatment for current malignant diseases, major psychiatric disorders (e.g. major depression, psychosis, bipolar disorder), other conditions preventing co-operation as judged by the local study nurse or consulted physician at the local study site; * Participation in any other research intervention trial at time of pre-screening and throughout the study period.
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What it tests

  • Personalized lifestyle intervention
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Where

2 sites
Alzheimer Center Amsterdam
Amsterdam, Netherlands
Maastricht University
Maastricht, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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