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Dextran 40 Plus Ringer's Lactate Vs. Ringer's Lactate Alone for Fluid Resuscitation in Acute Pancreatitis

RecruitingNAAges 18 Years - anyAllSatu Mare County Emergency Hospital
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In plain words

What the trial is, and whether it could suit you

This clinical trial aims to learn if a combination of Dextran 40 and Ringer's lactate solution can improve fluid resuscitation in mild and moderate acute pancreatitis (AP) and prevent complications. The main questions it aims to answer are: Does early fluid resuscitation with Dextran 40 plus Ringer's lactate improve patient outcomes compared to Ringer's alone? Does this treatment reduce inflammation, organ failure, and the need for intensive care unit (ICU) admission? Researchers will compare Dextran 40 plus Ringer's lactate to Ringer's alone to see if the combination therapy is more effective in reducing disease severity and complications. Participants will: Receive either Dextran 40 plus Ringer's lactate (1:3 ratio) or Ringer's lactate alone. Have blood tests every 24 hours to measure inflammation and organ function. Be monitored for changes in disease severity, need for ICU admiss

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * adults (โ‰ฅ18 years) diagnosed with mild or moderate acute pancreatitis * must provide written informed consent for study participation. Exclusion Criteria: * patients who decline to provide informed consent. * patients are non-compliant with treatment and follow-up visits. * pregnant individuals. * patients requiring concomitant treatment that is contraindicated within the study protocol. * patients who develop conditions that contraindicate the administration of the investigational medication. * patients experiencing severe adverse reactions necessitating treatment discontinuation.
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What it tests

  • Ringer lactate (RLS)
  • Dextran+Ringer Lactat(D+RLS)
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Where

1 site
Spitalul Judetean de Urgenta Satu Mare
Satu Mare, Romania
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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