🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Mepilex Lite Dressings for the Treatment of Acute Radiation Dermatitis of Anal Canal Skin

RecruitingNAAges 18 Years - anyAllQianfoshan Hospital
NCT06837831 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Background: According to GLOBOCAN 2022 statistics, colorectal cancer has become the third most common cancer disease worldwide, and also the second leading cause of death. The incidence rate of rectal cancer is particularly prominent. Radiotherapy is one of the important methods for comprehensive treatment of rectal cancer, but the radiation damage caused by radiotherapy cannot be ignored. During radiotherapy for rectal cancer, the skin of the anal canal will be damaged by radiation, resulting in acute radiation dermatitis, which is characterized by redness, pain, and ulcers. The main symptom of patients is anal pain. As the radiation dose accumulates, the skin damage to the anal canal becomes increasingly severe, and the patient's anal pain becomes more severe, which seriously affects the patient's quality of life. Mepilex Lite Dressings can absorb the exudate, keep it moist, promote th

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion criteria 1. Confirmed rectal cancer by histopathological diagnosis; 2. Individuals with clear indications for radiotherapy; 3. Individuals who receive radiation therapy for the first time and develop grade 2 or higher acute radiation dermatitis after receiving radiation therapy; 4. Age ≥ 18 years old; 5. Those who voluntarily participate in this study and sign the informed consent form. Exclusion criteria 1. Individuals with allergic constitution and allergies to the drugs and materials used in this study; 2. Those who withdraw or interrupt radiotherapy midway; 3. Individuals with mental illness, emotional instability, or inability to express their own feelings; 4. Individuals with various comorbidities such as serious cardiovascular and cerebrovascular diseases, digestive system diseases, hematological diseases, and infectious diseases; 5. Physical condition score (Eastern Cooperative Oncology Group, ECOG) \>3 points; 6. Individuals suffering from anal fissures and other diseases that cause skin damage to the anal canal; 7. Individuals with an artificial anus.
💊

What it tests

  • Control group
  • Experimental group
📍

Where

1 site
The First Affiliated Hospital of Shandong First Medical University
Jinan, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy