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Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease

RecruitingNAAges 18 Years - 80 YearsAllZhang longjiang,MD
NCT06843005 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The primary objective of this study is to evaluate whether a management strategy based on coronary computed tomography angiography (CCTA) for patients with non-obstructive coronary artery disease can improve the LDL-C target achievement rate compared to a traditional management strategy without follow-up CCTA, thereby reducing the incidence of major adverse cardiovascular and cerebrovascular events over a 3 years period, including all-cause mortality, myocardial infarction, ischemia driven revascularation and stroke.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age between 18 and 80 years old; 2. Known patients with non-obstructive coronary artery disease (disease duration ≥2 years); 3. Patients who agree to undergo follow-up CCTA examinations and cooperate in completing follow-up observations. Exclusion Criteria: 1. Patients who have experienced ACS or PCI/CABG; 2. Patients who have experienced adverse cardiovascular and cerebrovascular events; 3. Patients who have undergone follow-up CCTA or DSA examinations before enrollment; 4. Patients with severe hepatic and renal dysfunction; 5. Patients with contraindications to CCTA examinations; 6. Patients with poor initial CCTA image quality or data loss.
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What it tests

  • Coronary Computed Tomography Angiography
  • Current clinical guidelines
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Where

1 site
Research Institute Of Medical Imaging Jinling Hospital
Nanjing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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