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MOTION Clinical Trial

RecruitingNAAges any - anyAllMoximed
NCT06843980 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Prospective, multicenter, two-arm, 2:1 randomized controlled trial (RCT) comparing the benefits in subjects with medial knee osteoarthritis who are treated with either the MISHA Knee System or with non-surgical treatment. This is the first randomized head-to-head study comparing outcomes from subjects treated with the MISHA Knee System.

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📋 Eligibility rules (as published)
Key Inclusion Criteria: 1. Activity exacerbated knee pain isolated to the medial compartment and not global in nature 2. WOMAC pain ≥ 40 3. Failed to find relief in non-surgical treatment modalities Key Exclusion Criteria: 1. Large medial osteophyte(s) or considerable extruded meniscus that may interfere with the placement or function of the device 2. Poor bone quality (e.g., bony erosion, osteopenia, osteoporosis) 3. Ligamentous instability 4. Active or recent knee infection 5. Inflammatory joint disease, including sequelae of viral infections 6. Suspected or documented allergy or hypersensitivity to cobalt, chromium, nickel or other metals 7. History of keloid, hypertrophic or contracture scaring 8. Propensity for restrictive scar formation or adhesions with prior procedures
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What it tests

  • MISHA Knee System
  • Non-Surgical Treatment
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Where

9 sites
UC Davis Department of Orthopaedic Surgery
Davis, United States
Scripps Clinic Jefferson
Oceanside, United States
Sutter Health
Sacramento, United States
Rush University Medical Center
Chicago, United States
Genesis Orthopedics & Sports Medicine
Oak Brook, United States
University of Nebraska Medical Center
Omaha, United States
NYU Langone Health
New York, United States
Ohio State Jameson Crane Sports Medicine Institute
Columbus, United States

…and 1 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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