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The Effect of Different Risk Factors on the Success Rate of VPT

Recruitingn/aAges 18 Years - anyAllSemmelweis University
NCT06844448 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to evaluate the effectiveness of various vital pulp therapy (VPT) methods, such as direct pulp capping, partial pulpotomy, and total pulpotomy, in maintaining pulp vitality following pulp exposure. It explores the success rates of these treatments compared and investigates co-factors influencing these rates, including age. This prospective cohort study involves patients over 18 with restorable teeth and exposed pulp chambers. Success is measured through clinical and radiological criteria over a follow-up period of up to four years. The study also aims to identify if there's an age threshold affecting the preference for VPT over root canal therapy.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients over 18 years of age who have at least one tooth with a pulp chamber that has been opened during a dental procedure or is likely to be opened during restoration of the tooth * The tooth is responsive to a sensitivity test with cold spray * The coronal part must be restorable * The periodontal depth around the tooth should be 0 according to the Dental Practicality Index Periodontal Treatment Need, i.e. the probing depth around the tooth should not be greater than 3.5 mm Exclusion Criteria: * Internal/external resorption in the tooth * If the root development of the tooth is not yet complete or if it is a deciduous tooth * Absolute isolation cannot be performed during the procedure * If pulp exposure does not occur even after complete removal of caries * The crown of the tooth cannot be restored * Periodontium surrounding tooth affected by moderate/severe marginal periodontitis (probing depth deeper than 3.5 mm) * Pulp exposure due to traumatic injury * Baseline radiograph shows signs of severe pulp palcification * Periapical lesion is around the root (Periapical index of the tooth \>2)
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What it tests

  • with Biodentine
  • with MTA
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Where

1 site
Department for Restorative Dentistry and Endodontics, Semmelweis University
Budapest, Hungary
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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