🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Impact of Resistance Training Intensity on Blood Pressure

RecruitingNAAges 50 Years - 70 YearsFemaleUniversité de Sherbrooke
NCT06845514 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The goal of the clinical trial is to understand the effect of two resistance training protocols employing different loading intensities (% of 1 repetition maximum; 1-RM), but with standardized effort intensity (2 repetitions in reserve; RIR) on post-exercise and ambulatory blood pressure in aging females. The main questions it aims to answer are: * to examine the acute effects of low (50% 1-RM) and high (80% 1-RM) load intensity resistance exercise with a standardized high effort intensity on post-exercise hypotension and ambulatory blood pressure responses in aging females; * deepen the understanding of the mechanisms underlying acute reductions in blood pressure in response to resistance exercise performed at different load intensities. To this end, autonomic activity will be estimated alongside the measurement of central arterial compliance (i.e., carotid artery), and serum biomarke

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * aged 50 to 70 years; * absence of menstruation for 12 consecutive months; * normal-high resting blood pressure (120 ≤ Systolic ≤ 139 mmHg and 80 ≤ Diastolic ≤ 89 mmHg) or stage 1 hypertension (140 ≤ Systolic ≤ 159 mmHg or 90 \< Diastolic ≤ 99 mmHg); * physically inactive (\< 150 minutes of structured aerobic physical activity per week); * and not engaging in regular resistance exercise (≥ 2 sessions per week) for more than 3 months during the year. Exclusion Criteria: * orthopedic limitations or other contraindications to resistance exercise; * scheduled surgery during the study; * unstable hypertension (≥ 160/100 mmHg); * diagnosis of type 2 diabetes; * cardiovascular event in the past 6 months or sequelae preventing exercise; * and initiation of hormonal replacement therapy (\< 4 months) known to affect blood pressure.
💊

What it tests

  • Condition LL-RE
  • Control
  • Condition HL-RE
📍

Where

1 site
Research Center on Aging
Sherbrooke, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy