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Dose Efficacy in Adhesive Capsulitis

RecruitingPhase 3Ages 18 Years - anyAllUniversity Health Network, Toronto
NCT06848374 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to find out if the treatment of adhesive capsulitis with 40 mg of methylprednisolone in combination with a hydrodilatation is comparable to 80 mg of methylprednisolone for pain reduction, improving shoulder mobility, and reducing side effects. Researchers will enroll 40 people in this study which is taking place solely at the Toronto Rehabilitation Institute, University Avenue. This study should take approximately 12 months to complete and the results should be known in about 15 to 18 months. During this study, patients will receive an ultrasound guided shoulder hydrodilatation combined with corticosteroid after "randomized" into one of the groups (40 mg vs 80 mg). This is a double blind study as both patients and physicians would not know the group patient was randomized to. Pain scores, Range of Motion and few other questionnaires wold be completed to tra

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📋 Eligibility rules (as published)
Inclusion Criteria: * \>18 years of age * Diagnostic of adhesive capsulitis of the shoulder Exclusion Criteria: * Injection received in the affected shoulder \< 3 months ago (any kind) * History of previous surgery in the affected shoulder * Glenohumeral osteoarthritis more than mild on the xray * Pregnancy * Blood thinner (other than Aspirin 80 mg) or bleeding disorder * Active infection (requiring antibiotic) * Allergy to steroid or lidocaine * Cognitive impairment * Active litigation * Inflammatory connective tissue disorder
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What it tests

  • 40 mg Methylprednisolone
  • 80 mg Methylprednisolone
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Where

1 site
Toronto Rehabilitation Institution
Toronto, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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