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Tubeless Surgery With Impaired Pulmonary Function

RecruitingNAAges 14 Years - 85 YearsAllThe Second Hospital of Shandong University
NCT06848751 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Some patients with impaired lung function require minimally invasive surgical treatment, including those with lung cancer, benign lung tumors, pneumothorax, or lung volume reduction surgery. Patients with borderline lung function often cannot be extubated immediately postoperatively under conventional treatment models. These patients typically need to be transferred to the surgical ICU for close monitoring. However, positive-pressure mechanical ventilation with an endotracheal tube carries risks of further airway injury and persistent air leakage from the lung surface, leading to a high incidence of postoperative respiratory failure. Non-intubated minimally invasive surgery (tubeless), which preserves spontaneous breathing without endotracheal intubation, avoids the physical stimulation of intubation and the airway damage caused by mechanical ventilation. This approach may reduce the in

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients with impaired lung function (who may require postoperative intubation and transfer to the surgical ICU after preoperative and MDT discussions). 2. Patients requiring minimally invasive lung resection due to lung cancer, pulmonary nodules, benign lung tumors, pneumothorax, lung volume reduction surgery, etc. 3. Patients with normal mental status who can cooperate with perioperative examinations, exercises, and physical rehabilitation measures. 4. Patients who agree to participate in the clinical trial after communication. Exclusion Criteria: 1. Patients with severe impairment of cardiopulmonary function or other organ systems, who are deemed unable to tolerate any form of anesthesia or minimally invasive surgery after preoperative and MDT discussions. 2. Patients with abnormal mental status or who are unable to adequately cooperate with perioperative examinations, exercises, and physical rehabilitation measures. 3. Patients who refuse to participate in the clinical trial or decline the use of non-intubated anesthesia with preserved spontaneous breathing. 4. Patients who refuse to undergo surgery.
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What it tests

  • Non-intubated thoracoscopic surgery
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Where

1 site
The Second Hospital of Shandong University
Jinan, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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