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Investigation of the Relationship Between Central Sensitization and Balance in Fibromyalgia

Recruitingn/aAges 18 Years - 65 YearsFemaleSultan Abdulhamid Han Training and Research Hospi…
NCT06851091 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of the study is to investigate the relationship between central sensitization parameters and changes in static and dynamic balance in patients with fibromyalgia. The main questions it aims to answer are: * Do central sensitization parameters differ in patients with fibromyalgia compared to healthy individuals? * How is balance performance in these individuals compared to healthy controls? * Do central sensitization parameters affect static and dynamic balance in patients with fibromyalgia? * Do central sensitization parameters lead to quantitative changes in balance in patients with fibromyalgia?

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of FMS according to the ACR 2016 diagnostic criteria * Being between the ages of 18 and 65 * Being literate * Providing informed consent by signing the voluntary consent form Exclusion Criteria: * Being under 18 years old or over 65 years old * Presence of vestibular disorders * Having undergone spinal and/or extremity surgery (such as for back/hip/knee/foot) within the last 6 months * History of lower extremity amputation * Presence of spinal deformities * Peripheral arterial disease * Vitamin B12 deficiency * Any neurological disorder (e.g., stroke, traumatic brain injury, multiple sclerosis, Parkinson's disease, central nervous system malignancies, etc.) * Severe cardiopulmonary insufficiency (stage 3-4) * Uncontrolled systemic diseases such as hypertension and diabetes * Presence of systemic inflammatory diseases, malignancies, or active infections * Pregnancy
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What it tests

  • Biodex Balance System
  • Pressure Pain Threshold (PPT) Measurement with Algometer
  • Conditioned Pain Modulation (CPM)
  • Slowly Repeated Evoked Pain Assessment Protocol (SREP)
  • Central Sensitization Inventory (CSI)
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Where

1 site
Sultan 2. Abdülhamid Han Training and Research Hospital, İstanbul, Üsküdar
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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