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CD70-targeted immunoPET Imaging of Malignant Cancers

RecruitingPhase 2Ages 18 Years - 80 YearsAllRenJi Hospital
NCT06852638 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

This study aims to determine the value of cluster of differentiation (CD70)-targeted immuno-positron emission tomography/computed tomography (immunoPET/CT) imaging for diagnosing human malignancies, including renal cell carcinoma (particularly clear cell renal cell carcinoma), lymphoma, and nasopharyngeal carcinoma (NPC), among others.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Aged 18-80 year-old and of either sex๏ผ› * Histologically confirmed diagnosis of renal cancer (especially ccRCC)/lymphoma/NPC or suspected renal cancer/lymphoma/NPC by diagnostic imaging; * Capable of giving signed informed consent, including compliance with the requirements and restrictions in the informed consent form (ICF) and this protocol. Exclusion Criteria: * Pregnancy๏ผ› * Severe hepatic and renal insufficiency; * Allergic to single-domain antibody radiopharmaceuticals.
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What it tests

  • [18F]F-RESCA-RCCB6
  • [18F]F-RESCA-R8B4
  • [68Ga]Ga-NOTA-R8B4
  • [18F]F-RESCA-RD06
  • [68Ga]Ga-NOTA-RD06
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Where

1 site
Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Shanghai, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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