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โ† Trials
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FeNO Detection in Asthma Diagnosis: A New Technology Approach

RecruitingNAAges 18 Years - anyAllNovlead Inc.
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In plain words

What the trial is, and whether it could suit you

The detection of exhaled nitric oxide (FeNO) represents a non-invasive, safe, and rapid approach for assessing endogenous nitric oxide (NO) levels within the airway. FeNO concentrations are closely associated with airway inflammation and hyperresponsiveness, and are currently recognized as biomarkers indicative of type II airway inflammation. Recent advancements in nitric oxide detection technology for both upper and lower airways, as well as for small and large airways, have provided significant insights for the diagnosis and management of conditions such as bronchial asthma, chronic cough, upper airway diseases, chronic obstructive pulmonary disease, and even rare airway disorders. Presently, FeNO measurement is frequently employed in the differential diagnosis and monitoring of airway inflammatory diseases. The FeNO test is conducted using a FeNO test analyzer. Internationally, FeNO

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Patients: Inclusion Criteria: 1. Participants must be a minimum of 18 years of age, irrespective of gender; 2. Individuals must possess a diagnosis of bronchial asthma that aligns with the international GINA 2023 diagnostic criteria; 3. Respiratory symptoms must have been evident for at least 6 weeks; 4. Participants should either have no history of smoking or have discontinued smoking for a period exceeding 5 years. Exclusion Criteria: 1. The concurrent use of additional asthma medications (such as glucocorticoids) alongside short-acting bronchodilators within the prior 4 weeks; 2. A diagnosis of respiratory infection within the preceding 4 weeks; 3. Conditions such as pregnancy, lactation, or menstruation; 4. Participation in other clinical research studies; 5. Any underlying medical or psychiatric conditions that, in the investigator's assessment, would render the individual unsuitable for participation in the study. Healthy: Inclusion Criteria: 1. Participants must be at least 18 years of age, with no restrictions on gender; 2. Individuals should not have a history of allergic diseases or chronic respiratory conditions, and must not exhibit any significant abnormalities in health assessments conducted within the past year; 3. There should be no acute illnesses or medication history within the preceding four weeks, and participants must not display any typical symptoms of respiratory infections; 4. A history of smoking is not permitted, or individuals must have ceased smoking for a minimum of five years. Exclusion Criteria: 1. Individuals who are pregnant, breastfeeding, or currently experiencing menstruation; 2. Those who have been on long-term medication; 3. Participants involved in other clinical research studies; 4. Any potential medical or psychological conditions that the researcher deems may render the subject unsuitable for participation in the study.
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What it tests

  • Chemiluminescent FeNO Analyzer
  • Electrochemical FeNO Analyzer
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Where

2 sites
Ruijin Hospital
Shanghai, China
Wuxi Xinwu District Xinrui Hospital
Wuxi, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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