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Effects of Ultra Processed Food on Intestinal Energy Harvest

RecruitingNAAges 25 Years - anyAllColumbia University
NCT06853288 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Ultra processed food is everywhere in modern society and may contain multiple ingredients that affect the way participants' bodies store energy. Some studies have shown that eating a diet high in ultra processed foods leads to weight gain, but these foods have not been studied enough to understand why. Recently, the gut microbiome has become a potential way to measure energy balance in the human body; this is done by measuring how many calories are in the stool. The investigators propose to test a very high ultra-processed food diet where 80% of calories are coming from ultra processed food and a low ultra processed food diet where 20% of the calories are coming from ultra processed food. This study will compare stool sample energy content of the two diets.

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📋 Eligibility rules (as published)
Inclusion Criteria: * BMI 30-40kg/m2 * weight stable * able to download app and willing to use it for duration of study * does own grocery shopping * otherwise healthy Exclusion Criteria: * pregnancy * history of or planned bariatric surgery * history of anti obesity medications
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What it tests

  • Diet containing 80% ultra processed foods
  • Diet containing 20% ultra processed foods
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Where

1 site
Columbia University Irving Medical Center
New York, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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