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Early Evaluation of Exosome Multiomics and Clinical Prognosis in Patients With Sudden Death

Recruitingn/aAges 18 Years - anyAllThe Affiliated Nanjing Drum Tower Hospital of Nan…
NCT06856993 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Acute coronary syndrome (ACS) is one of the main causes of death. Worldwide, tens of millions of patients are hospitalized for coronary heart disease and ACS every year. ACS may show acute myocardial infarction, unstable angina pectoris, and even induce early arrhythmia, leading to sudden death. Sudden cardiac death (SCD) has a strong correlation with ACS. Data from clinical and autopsy studies and death certificates show that 62-85% of patients with out of hospital SCD have a history of ACS, 10% have other cardiac structural abnormalities, and 5% have no cardiac structural abnormalities. An SCD surveillance study from Ireland concluded that most cases occurred in families, and the successful recovery of SCD was mainly related to ventricular fibrillation with arrhythmia. At present, there are few reports on the clinical and prognosis of ACS in China, and there is no guideline or consensu

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📋 Eligibility rules (as published)
Inclusion Criteria: * The death event happens suddenly. * Age ≥ 18 years * The patient had obvious clinical symptoms 24 hours before treatment * Life expectancy exceeds 3 days * Proxy of patients signs the informed consent form * Comply with ACS diagnostic indicators recommended by ACC / AHA guidelines in 2016 Exclusion Criteria: * Death caused by accident, such as trauma, poisoning, etc. * Death from accidental or intentional overdose * Death from asphyxia * Death is caused by chronic disease or terminal illness * The patient died naturally * Has participated in other clinical studies * Immediate family members give up continuing treatment
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What it tests

  • standardized medical care of cardiac arrest
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Where

1 site
Nanjing Drum Tower Hospital
Nanjing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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