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Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia

Recruitingn/aAges 18 Years - 99 YearsAllNovartis Pharmaceuticals
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In plain words

What the trial is, and whether it could suit you

This study has the purpose to answer how the Lipoprotein(a) (Lp(a)) level is distributed among Atherosclerotic cardiovascular disease (ASCVD) patients in Russia, and what is the connection between elevated levels of this parameter and the cardiovascular disease (CVD) risk.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: 1. Written informed consent (signed and dated). 2. Males and females aged ≥18 years. 3. Presence of one of the following ASCVDs for at least 3 months within the 2 years prior to signing the informed consent to participate in this study: * history of MI; * history of IS and/or TIA; * IHD confirmed by coronary angiography (stenosis ≥50%); * any revascularization surgery (emergency or planned), including CABG, PCI, carotid endarterectomy or carotid/intracranial stenting; * peripheral artery disease (intermittent claudication with ankle-brachial index ≤0.90 and/or lower limb amputation or revascularization in case of lower limb ischemia). Exclusion Criteria: 1. Acute infectious and inflammatory diseases, such as COVID-19, in the month leading up to the Screening visit. 2. Lp(a)-lowering therapy/methods (Lp(a) apheresis with PCSK9 inhibitors, inclisiran prior to the Screening visit) in the medical history before the Screening visit. 3. Participation in any interventional clinical study with investigational or marketed medicinal products at the time of enrollment. 4. Participation in other real-world clinical studies. 5. Stages 4 and 5 of chronic kidney disease (glomerular filtration rate CKD-EPI \<30 mL/min/1.73 m2) and/or hepatic disease (total bilirubin: 2 × ULN). Other protocol-defined inclusion/exclusion criteria may apply.
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What it tests

  • Atorvastatin
  • Simvastatin
  • Rozuvastatin
  • Ezetimibe
  • Niacin
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Where

20 sites
Novartis Investigative Site
Chelyabinsk, Russia
Novartis Investigative Site
Chelyabinsk, Russia
Novartis Investigative Site
Kaluga, Russia
Novartis Investigative Site
Kemerovo, Russia
Novartis Investigative Site
Krasnoyarsk, Russia
Novartis Investigative Site
Moscow, Russia
Novartis Investigative Site
Moscow, Russia
Novartis Investigative Site
Moscow, Russia

…and 12 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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