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Prevention of Clostridium Difficile Infections Using Lactobacillus Plantarum 299v Strain in Nephrology and Transplantation Department

RecruitingNAAges 18 Years - anyAllMedical University of Silesia
NCT06859437 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this study was to analyze whether the use of the LP299v strain reduces the risk of Clostridium difficile infection (CDI) among patients receiving antibiotics and hospitalized in the nephrology and transplantation ward. Adutt patients from risk group (receiving immunosuppressive drugs and treated with antibiotics) were enrolled into study. Patients who meet the above criteria for inclusion in the study will be assigned to one of two groups. Patients in group I (study) will receive a probiotic containing the Lactobacillus plantarum 299v strain of bacteria as part of the prophylaxis of Clostridioides difficile infection. The daily dose is 1 capsule containing approximately 10x109 colony-forming units of live bacteria taken orally with a meal. Patients in group II (control) will receive a placebo. The duration of probiotic or placebo use will be 3 months. Assignment to groups I

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📋 Eligibility rules (as published)
Inclusion Criteria: * over 18 years old * organ transplantation or receiving immunosuppressive drugs for any other reasons * antibiotics therapy Exclusion Criteria: * no consent to participate in the study
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What it tests

  • Prevention of C. difficile infections using LP299v strain Placebo
  • Prevention of C. difficile infections using LP299v strain LP299v
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Where

1 site
Department of Nephrology, Transplantation and Intenal Medicine Medical University of Silesia
Poland, Poland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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