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Cryo Nerve Block Trial

RecruitingNAAges 18 Years - anyAllSt. Antonius Hospital
NCT06861387 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Background: Minimally invasive lung surgery, such as video-assisted thoracoscopic surgery (VATS) or robot-assisted thoracoscopic surgery (RATS), has become more common for lung resections because it leads to faster recovery, less pain, and shorter hospital stays. However, pain after surgery remains a major issue. Current guidelines suggest using a combination of pain management strategies to reduce the use of opioids and their side effects. Intercostal cryo-analgesia (ICCA), a technique that uses cold to reduce nerve activity, may help lower pain and opioid use after surgery. However, there is limited research on ICCA, with most studies having small sample sizes and lacking randomized controlled trials. More research is needed to compare ICCA with standard pain management in patients undergoing minimally invasive lung surgery. Objective: The goal of this study is to determine whether

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients are at least 18 years or older. 2. Patients are electively scheduled to undergo minimally invasive (i.e., VATS or RATS) anatomical lung (i.e., pneumonectomy, (bi)lobectomy, or segmentectomy) resection for benign or malignant disease. 3. Proficient understanding of the consequences of enrolment by the patients. 4. Written informed consent by the patient. Exclusion Criteria: 1. Patients with reported intolerance or hypersensitivity to the anaesthetic drug used for ICNB. 2. Patients chronically using opioids for reasons not related to the operation (i.e., more than 3 months). 3. Patients with liver failure inhibiting the systematic use of acetaminophen (i.e., paracetamol) 4. Patients with connective tissue disease. 5. Patients with comorbidities or history contra-indicating ICCA. 6. Patients who are pregnant. 7. Participation in other clinical trial(s) that may interfere with the current trial.
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What it tests

  • Cryotherapy
  • PAiN - multimodal analgesia
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Where

1 site
St. Antonius Ziekenhuis
Nieuwegein, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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