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Early Detection of CTEPH in Patients After APE

Recruitingn/aAges 18 Years - anyAllInstitute of Health Information and Statistics of…
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In plain words

What the trial is, and whether it could suit you

The project is a national, prospective, multicenter, observational pilot project of screening CTEPH in pacients after APE in the Czech Republic. The main goal of the project is to methodically prepare, implement and evaluate a pilot project that will verify the suitability of the proposed procedure of early detection of Chronic tromboembolic pulmonary hypertesion in such a way as to ensure the maximum positive impact on the health of the population and high cost-effectiveness of the whole process.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Age over 18 years * Signed consent to participate in the project and GDPR * Patients with an episode of acute pulmonary embolism in the last 3-12 months, with ongoing anticoagulation therapy: 1. Patients with new-onset and ongoing or progressive dyspnea (min. NYHA II) after a pulmonary embolism episode or worsening of dyspnea after a pulmonary embolism episode compared to the status before the episode (at least 1 HYHA grade) or 2. Asymptomatic patients after a pulmonary embolism episode and at least one of the following risk factors: * ECHO evidence of severe PH at diagnosis of PE (PASP \>60 mmHg) * Antiphospholipid syndrome with triple positivity (presence of lupus anticoagulans + anti-beta-2-glycoprotein I (B2GPI) antibodies + anticardiolipin) * Infected permanent venous inlets and cardiac pacing/defibrillation intravascular systems * Presence of ventriculoatrial shunt for treatment of hydrocephalus * Nonspecific intestinal inflammation (ulcerative colitis, Crohn's disease) * History of splenectomy * Myeloproliferative disorders * Chronic osteomyelitis Exclusion Criteria: * Not agreeing to participate in the project * Contraindications to treatment
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What it tests

  • Standardized CTEPH Screening Protocol
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Where

10 sites
Brno University Hospital
Brno, Czechia
Havlíčkův Brod Hospital
Havlíčkův Brod, Czechia
University Hospital Hradec Králové
Hradec Králové, Czechia
Jihlava Hospital
Jihlava, Czechia
Náchod Hospital
Náchod, Czechia
University Hospital Olomouc
Olomouc, Czechia
University Hospital Ostrava
Ostrava, Czechia
Pardubice Hospital
Pardubice, Czechia

…and 2 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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