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Hybrid Prehabilitation Before Thoracic Surgery

RecruitingNAAges 18 Years - anyAllADIR Association
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In plain words

What the trial is, and whether it could suit you

Background and study aims: Lung cancer is a leading cause of cancer-related deaths worldwide. Patients with non-small cell lung cancer often undergo lung surgery to remove the tumor. Before surgery, patients may participate in prehabilitation programs to improve their physical fitness and overall health, which can lead to better surgical outcomes. Traditionally, these programs are conducted entirely in specialized centers, but places are scarce, limiting access. This study aims to compare the relative effectiveness of a hybrid prehabilitation program, combining home-based and center-based sessions, with the standard center-based program. The primary goal is to assess changes in aerobic capacity, measured by peak oxygen uptake, before and after participation in the prehabilitation program. Who can participate? Adults over 18 years old who are scheduled for lung resection surgery to tre

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age \> 18 years * Patient scheduled to undergo lung resection for the treatment of diagnosed or suspected bronchial cancer * Referred for prehabilitation before lung resection surgery * Patient living at home with another adult present during exercise sessions * Surgery date not established at the time of inclusion in the program, or at least 4 weeks away * Peak oxygen uptake below 20 ml/kg/min * Affiliated with a health insurance system * Able to read and understand the information letter and sign the consent form Non-Inclusion Criteria\*: * Oxygen therapy during exercise * Cardiological contraindication to exercise training * Refusal to participate in a center-based prehabilitation training program * Orthopedic, neurological, vascular, or neuromuscular conditions limiting exercise training on a cycle ergometer * Patient under guardianship or curatorship * Pregnant or breastfeeding women Exclusion Criteria: -Withdrawal of consent \*The eligibility criteria were revised in May 2026 following approval of a protocol amendment by the French Ethics Committee (CPP รŽle-de-France IV). The former non-inclusion criterion of patients receiving concomitant neoadjuvant chemoradiotherapy was removed to better reflect the study population to current clinical practice, as neoadjuvant treatments are increasingly integrated into the care pathway of patients undergoing thoracic surgery for non-small cell lung cancer and referred for pulmonary prehabilitation. The previous restriction had been too limiting and had slowed recruitment. This amendment was proposed to improve the feasibility of recruitment and to increase the representativeness of the study population, while ensuring the safety of the participants as no additional safety concerns were identified and all other exclusion criteria related to safety were unchanged.
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What it tests

  • Hybrid prehabilitation
  • Center-based prehabilitation
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Where

1 site
Association ADIR
Rouen, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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