European Registry of Next Generation Imaging in Advanced Prostate Cancer

Inclusion Criteria: 1. Adult male patients (≥18 years with no upper age limit). 2. Histologically proven prostate cancer. 3. Patients who require imaging exploration (conventional, Next-Generation Imaging (NGI), or their combination) at high risk for harbouring metastatic deposits at the hormone-sensitive stage, either at the diagnostic workout of a "naïve" patient or at biochemical relapse/progression after local treatment. 4. Patients who authorize their participation in the study by signing a written informed consent form (ICF). Exclusion Criteria: 1. Patients participating in other interventional or non-interventional study which requires NGI as a triage test for metastatic assessment. 2. Patients with evidence of any other clinically significant disease or condition which in the opinion of the investigator discourages their participation in the study. 3. Patients who will not be able to complete the study.