AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Effectiveness of Decision Support for Cardiovascular Risk Management in People With Cardiovascular Disease

RecruitingNAAges 40 Years - 80 YearsAlldr.Frank L.J. Visseren
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

This study aims to improve the way patients with cardiovascular diseases are informed about their treatment options. It explores methods to support shared decision-making between patients and doctors. In some cases, doctors will take extra time to discuss treatment options in detail. To assess the impact, some patients will be asked to complete questionnaires after their clinic visits.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion criteria: * Established ASCVD * At least 30 days since last CVD event and/or the diagnosis of ASCVD. If no CVD events have occurred, imaging confirming ASCVD must have been conducted at least 30 days prior. * Documented ASCVD (defined according to the 2021 European Society of Cardiology guideline), which includes ASCVD established clinically or demonstrated unequivocally by imaging: * Clinically documented ASCVD includes previous myocardial infarction, acute coronary syndrome, coronary revascularization (Percutaneous Coronary Intervention (PCI) or Coronary Artery Bypass Surgery (CABG)), and other arterial revascularization procedures, ischemic stroke or transient ischemic attack, and peripheral artery disease (from Fontaine stage II). Angina pectoris (stable) without imaging evidence of atherosclerosis does not qualify as ASCVD. * ASCVD unambiguously identified through imaging, includes significant stenosis (\>50%) on coronary angiography, computed tomography angiography, or carotic ultrasound. It also includes aortic aneurysms measuring โ‰ฅ3cm. Only Carotid Intima-Media Thickness measurements (cIMT), Coronary Artery Calcium scoring or abnormal ankle-brachial index scores without evidence of stenosis, do not qualify as ASCVD. * Age 40-80 years (to allow for individual risk predictions with the SMART2 model * Patient attending the Cardiology or Vascular Medicine outpatient clinic * Sufficient understanding of the Dutch language (due to the questionnaires being administered in Dutch). * Written informed consent must be provided. Although the proposed intervention is not subject to the WMO, informed consent is required for the collection and processing of data, including the distribution of questionnaires. Exclusion criteria: * Patients currently participating in other interventional medication studies, or studies that directly affect the therapy plan * Remaining life expectancy of less than 2 years as assessed by a consulting healthcare professional (these patients have no indication for cardiovascular risk management) * Patients for whom individual risk predictions with the SMART2 model are not feasible: * Systolic Blood Pressure (SBP) \<90 mmHg or \>200 mmHg * Total cholesterol \<2.5mmol/L or \>8 mmol/L * High-Density Lipoprotein (HDL) cholesterol \<0.6mmol/L or \>2.5 mmol/L * Low-Density Lipoprotein (LDL) \<0.1 mmol/L or \>7.4 mmol /L * Estimated Glomerular Filtration Rate (eGFR) \<30ml/min/1.73m2 or dialysis * Active treatment for malignity, pregnancy, history of organ transplantation, or liver failure * Previous participation in 2-DECIDE
๐Ÿ’Š

What it tests

  • 2-DECIDE intervention: decision support for cardiovascular risk management
  • No Intervention: usual care
๐Ÿ“

Where

8 sites
Noordwest Ziekenhuisgroep
Alkmaar, Netherlands
Meander Medisch Centrum
Amersfoort, Netherlands
Deventer Ziekenhuis
Deventer, Netherlands
Ziekenhuis Gelderse Vallei
Ede, Netherlands
Radboudumc
Nijmegen, Netherlands
HagaZiekenhuis
The Hague, Netherlands
Diakonessenhuis
Utrecht, Netherlands
UMC Utrecht
Utrecht, Netherlands
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy