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Acellular Collagen Matrix as a Tool to Obtain Wound Closure Following a Guided Bone Regeneration Procedure

Recruitingn/aAges 21 Years - 75 YearsAllOhio State University
NCT06871735 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Guided bone regeneration (GBR) is a procedure used to increase the amount of bone volume in the jaw before placing a dental implant. It is needed when a lot of bone has been lost around the spot where a tooth has been lost or extracted. An incision is made, bone grafting material is placed in that spot, there is a membrane put over it as a barrier, then gum tissue has to be pulled back over it. Usually, this is enough to cover the whole wound, but sometimes the barrier membrane can't be covered with tissue the whole way without too much pulling, and the barrier membrane is still exposed. In that case, one thing that can be done is to place another material, an acellular collagen matrix, over the barrier membrane and secure it there. This material has been shown to help with the healing in these cases. Participants in this study will be clinic patients who have been determined to need

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📋 Eligibility rules (as published)
Inclusion Criteria: * Have a missing tooth or teeth which are planned to be replaced with an implant * Need for guided bone regeneration procedure to increase the bone available for implant placement * Systemically healthy with no contraindications for bone grafting and/or implant surgery * No chronic sinus problems * Non-smoker * No need for removable temporary restorations during wound healing. Exclusion Criteria: * Patients that have sufficient bone volume to perform implant placement through conventional drilling protocol without any pre-implant GBR procedure * Indications for pre-implant/pre-GBR soft tissue grafting procedure to increase existing soft tissue contours * The need to wear a removable temporary restoration during healing
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What it tests

  • Acellular matrix
  • Surgical closure
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Where

1 site
The Ohio State University Graduate Periodontics Clinic
Columbus, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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