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Early Intra-aortic Balloon Pump Use After Venoarterial Extracorporeal Membrane Oxygenation

RecruitingNAAges 18 Years - anyAllBeijing Anzhen Hospital
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In plain words

What the trial is, and whether it could suit you

The goal of this multicenter, randomized trial is to compare early early left ventricular unloading by Intra-aortic Balloon Pump (IABP) versus conventional approach in patients with cardiogenic shock (CS) undergoing venoarterial extracorporeal membrane oxygenation (VA-ECMO). The main question it aims to answer is : • If left ventricular unloading by IABP as compared with the conventional approach will improve the outcomes in patients undergoing VA-ECMO.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age of ≥18 2. Cardiogenic shock(defined as a systolic blood pressure of less than 90 mm Hg for more than 30 minutes or the initiation of catecholamines to maintain a systolic pressure of more than 90 mm Hg, an arterial lactate level of more than 3 mmol per liter, and signs of impaired organ perfusion) 3. Successful implantation of VA-ECMO 4. Informed consent Exclusion Criteria: 1. SCAI shock stage A or B 2. Presence of moderate to severe aortic insufficiency or aortic dissection 3. Severe peripheral vascular disease 4. Post-cardiotomy cardiogenic shock(non-CABG procedure) or bridging to cardiac procedure(heart transplantation or LVAD). 5. VA-ECMO for definite non-cardiac causes 6. Isolated right ventricular failure 7. V-A ECMO usage confined to the period during surgery or other interventions 8. Ischemic mechanical complications(eg Ventricular septal defect, papillary muscle rupture) 9. Extracorporeal cardiopulmonary resuscitation 10. LVAD, Impella or IABP in situ. 11. Severe bleeding 12. Terminal malignancy 13. Irreversible neurologic injury 14. Pregnancy or lactation
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What it tests

  • Early IABP use
  • Conventional approach
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Where

1 site
Beijing Anzhen Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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