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Non-invasive Brain Stimulation to Prepare the Patient for Bariatric Surgery (REBAS)

RecruitingNAAges 18 Years - 65 YearsAllMasaryk University
NCT06874309 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Obesity is a chronic metabolic condition characterized by excessive accumulation of body fat, which triggers physiological mechanisms that increase the risk of a wide range of health problems. The most effective treatment for severe obesity is metabolic-bariatric surgery, which can lead to a 15-20% weight reduction, significantly lowering the risks of illness and death. However, the success of this surgery can be threatened by poor eating habits after the procedure. The main goal of this study is to enhance the long-term effectiveness of bariatric surgery by combining it with non-invasive brain stimulation (tDCS) targeting inhibitory centers before the operation. Additionally, the investigators aim to comprehensively monitor patients before and after surgery, focusing on investigating changes in brain function associated with the achieved weight loss.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Subjects with severe or morbid obesity (determined by BMI \> 35 or 40 kg/m2, respectively) eligible for BS treatment in compliance with the current guidelines * Subjects who meet reduced control over eating behavior (disinhibition) criteria in the Eating Habits Questionnaire Exclusion Criteria: * Subjects unable to provide informed consent and those unable to understand and cooperate with study-related procedures (based on the physician's discretion) * Subjects with a personal history of ischemic heart disease, myocardial infarction, stroke, heart failure, and atrial fibrillation * Subjects who have already undergone BS treatment in the past * Pregnant subjects or subjects that plan on becoming pregnant during the study. * Subjects deemed unsuitable for the study based on expert evaluation (e.g., by a physician or neuropsychologist) will be excluded. * Subjects with dreadlocks (problematic for the EEG)
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What it tests

  • home-based tDCS stimulation
  • home-based tDCS stimulation - sham
  • Bariatric surgery
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Where

2 sites
Saint Anne's University Hospital
Brno, Czechia
Central European Institute of Technology Masaryk University
Brno, Czechia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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