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An Extension Test of Whether to Use Oral Anti-anxiety Drugs (Alprazolam) When Patients Choose Second Eye Cataract Surgery After Unblinding, and Analyze Their Anxiety, Satisfaction and Pain Satisfaction

RecruitingPhase 4Ages 18 Years - 80 YearsAllNational Taiwan University Hospital
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In plain words

What the trial is, and whether it could suit you

Phacoemulsification is one of the most used surgical methods for cataract surgery today, and the surgeries are under the anesthetic and sedative to make it comfortable and safe for patients. The most important issue is which method is the best for reducing the patient's anxiety, pain, and discomfort during surgery. Previous studies have analyzed the impact of intravenous injection of sedative on the quality of phacoemulsification surgery; however, the impact of oral anti-anxiety drugs (Alprazolam) on cataract surgery has not been intensively studied. Therefore, the purpose of this study is to investigate the impact of Alprazolam on satisfaction in cataract surgery. Oral sedation is more convenient and safer than intravenous sedation. Therefore, the investigators will further analyze whether patients using oral anti-anxiety drugs will have an improvement in the pain, anxiety, overall sati

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Age between 18 and 80 years old. 2. Enrolled in "Anxiety and surgery satisfaction for cataract patient with different state anxiety" (Research Ethics Committee Case No.: 202302067MINB). 3. Plan to undergo phacoemulsification and intraocular lens implantation surgery with topical anesthetic on the second eye at the Department of Ophthalmology. 4. Subject who does not have side effect from XANAX. Exclusion Criteria: 1. Presence of any surgery contraindications. 2. Presence of any medication contraindications. 3. Inability to provide clear and complete answers to relevant questionnaires, or expression of no preoperative anxiety during the outpatient visit, or scores below 21 on the STAI-S or STAI-T assessment. 4. Regular use of anti-anxiety medications, sleeping pills, or analgesics before the procedure. 5. Pregnancy or breastfeeding during the preoperative period. 6. Severe corneal diseases, overripe cataracts, small pupils, or lens dislocation leading to difficulties in conventional surgery. 7. Patients under surface anesthesia who cannot fully cooperate with the surgical procedure. 8. Pregnant or uncertain pregnancy status (women under 55 years old to be verbally asked by research team members).
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What it tests

  • Alprazolam (Xanax)
  • Placebo Tablets
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Where

1 site
National Taiwan University Hospital
Taipei, Taiwan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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