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Effect of Pediatric Lung Ultrasound on Antibiotic Prescriptions in Hospitalized Children and Adolescents With Lower Respiratory Tract Infections. A Randomized Controlled Trial.

RecruitingNAAges 3 Months - 18 YearsAllAmerican University of Beirut Medical Center
NCT06876766 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Title: Effect of Pediatric Lung Ultrasound on Antibiotic Prescriptions in Hospitalized Children and Adolescents with Lower Respiratory Tract Infections (PLUS-AP Trial) Purpose of the Study: This study is being done to find out if a type of imaging called lung ultrasound (LUS) can help doctors decide when to stop antibiotics in children and teens who are in the hospital with lung infections, like pneumonia. Antibiotics are often given to these patients, but sometimes they are used for longer than necessary, which can be harmful. The investigators want to see if using LUS helps doctors make decisions that reduce unnecessary antibiotic use, which can help prevent antibiotic resistance and other complications. What is Lung Ultrasound (LUS)? Lung ultrasound is a safe, non-invasive, and painless test that uses sound waves to look at the lungs. It doesn't involve radiation like chest X-rays.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age between 3 months and 17 years old inclusive * Currently admitted to the pediatric Ward or boarding in the Emergency Department within 24 hours of admission order due to lower respiratory tract infections. Exclusion Criteria: * Sickle cell disease (SCD). * On chemotherapy or any other immunosuppressive therapy except systemic corticosteroids use of ≤ 5 days duration. * Cystic fibrosis and other chronic lung diseases except asthma * Pre-existing and/or congenital neurologic, metabolic, and cardiac conditions * Hospitalized within the previous month * Patients with suspected foreign body aspiration -Received antibiotic therapy within the previous week * Patients admitted under PI's care
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What it tests

  • Lung Ultrasound
  • Sham
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Where

1 site
American University of Beirut Medical Center
Beirut, Lebanon
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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