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High-Flow Nasal Oxygen for Preoxygenation in Emergency Surgery Patients With Full Stomachs

RecruitingNAAges 18 Years - anyAllNguyen Dang Thu
NCT06879600 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Patients with full stomachs face a high risk of regurgitation and aspiration under general anesthesia. To minimize the time between the loss of airway protective reflexes and successful tracheal intubation, rapid sequence induction intubation is commonly used. However, these patients are particularly vulnerable to hypoxemia during anesthesia induction, especially in emergency cases. Pre-oxygenation before induction is crucial for ensuring patient safety during apnea. High-flow nasal oxygen (HFNO) therapy, which consists of an air/oxygen blender, an active humidifier, and a single heated circuit, has recently gained widespread use in intensive care units (ICUs) for managing hypoxemic respiratory failure. HFNC can deliver a constant fraction of inspired oxygen (FiO₂) from 0.21 to 1.0 at high flow rates (up to 60 L/min or higher). Its advantages include generating continuous positive airwa

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📋 Eligibility rules (as published)
Inclusion Criteria: * Emergency surgical patients at risk of gastric fullness requiring endotracheal intubation. * Patients aged 18 years or older. * Health status classified as ASA I or II. * Mallampati classification I or II. Exclusion Criteria: * Patients with a predicted difficult airway, facial deformities, or an inability to achieve a proper mask seal. * Patients with respiratory diseases. * Pregnant patients. * Patients allergic to anesthesia or resuscitation drugs. * Patients who do not consent to participate in the study.
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What it tests

  • High-flow nasal cannula therapy application
  • Traditional facemask
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Where

1 site
Department of Anesthesia, Phu Tho General Hospital
Viet Tri, Vietnam
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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