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Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness/Implementation Hybrid Study

RecruitingNAAges 15 Years - 24 YearsAllNorthwestern University
NCT06880224 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Two combination interventions (HIV Case Finding Intervention and HIV Treatment Intervention), each with mHealth and Peer Navigation components, will be evaluated in two 48-week parallel hybrid effectiveness/implementation trials among youth aged 15-24 in Nigeria.

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📋 Eligibility rules (as published)
Inclusion Criteria: HIV Case Finding Intervention: * Aged 15 to 24 * Male birth sex of any current gender identity * Understand basic English, Yoruba, Hausa, Igbo or Pidgin English For the PrEP component, must also be HIV-negative HIV Treatment Intervention: * Aged 15 to 24 * HIV seropositive * Initiating ART for the first time at a Clinical Research Performance Site (CRPS) clinic or satellite clinic * Understand basic English, Yoruba, Hausa, Igbo or Pidgin English * Intention to remain a CRPS patient during follow-up Exclusion Criteria: * Unable to provide consent * No parental permission if aged 15 and not emancipated
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What it tests

  • Testing Peer navigation
  • PrEP Intervention
  • Treatment Peer Navigation
  • Social Media Outreach
  • SMS Test messaging
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Where

6 sites
University of Uyo Teaching Hospital
Uyo, Nigeria
Federal Medical Center
Makurdi, Nigeria
Taraba State Specialist Hospital
Jalingo, Nigeria
University of Nigeria Teaching Hospital
Enugu, Nigeria
Aminu Kano Teaching Hospital
Kano, Nigeria
Lagos University Teaching Hospital
Lagos, Nigeria
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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