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Reproducibility of Multiparametric Renal Magnetic Resonance Imaging on 1.5T MRI Scanners

RecruitingNAAges 18 Years - 70 YearsAllMario Negri Institute for Pharmacological Research
NCT06884410 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is an interventional, multicenter, prospective study involving healthy volunteers, to primarily assess the reproducibility of multiparametric renal MRI on 1.5T scanners. The study is also aimed at assessing possible differences in renal MRI reproducibility on 1.5T MRI scanners by sex and age, and assessing possible differences in renal MRI reproducibility across field strengths (1.5T vs 3T) in the subgroup of subjects enrolled in both RESPECT clinical study and in the current subproject.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Provision of written informed consent prior to any study specific procedures * Male and female subjects aged \[18-70\] years * Office SBP values \< 140 mmHg and DBP values ≤ 90 mmHg, under no antihypertensive therapy * Normal renal function defined as: estimated glomerular filtration rate \[eGFR\] ≥ 60mL/min/1.73m2 (using CKD-EPI Creatinine Equation) * Negative result upon urine testing for haematuria or proteinuria. Exclusion Criteria: * Previous enrollment in the present substudy * Contraindications to MRI including caustrophobia, pregnancy, cardiac pacemakers or other MRI-incompatible prostheses * Ongoing therapy (e.g. for diabetes, dyslipidemia, or any acute disease) * Past or current oncological pathology
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What it tests

  • MRI
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Where

4 sites
Aarhus University Hospital
Aarhus, Denmark
University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University
Mannheim, Germany
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Italy
Clínica Universidad de Navarra
Pamplona, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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