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Strategies to AchieVe Viral Suppression for Youth With HIV

RecruitingNAAges 12 Years - 30 YearsAllJohns Hopkins University
NCT06886971 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Although there have been advances in antiretroviral treatment (ART) for HIV, adolescents and young adults living with HIV (AHIV) continue to have disparate HIV outcomes particularly viral suppression (VS), when compared to other populations likely related to multi-layered challenges (social determinants, cognitive development), system, and biomedical challenges including the reliance on oral ART as the only choice for HIV treatment. Given that approximately 1/3 of AHIV despite being in care fail to attain or sustain VS with resultant individual and public health risk, there is a need to develop real-world implementable interventions that can improve the participants virologic outcomes. The Strategies to AchieVe Viral Suppression for Youth with HIV (SAVVY) Study aims to 1) optimize personal ART choice by using the HIV-ASSIST clinical program to inform CHOICE counseling regarding an AHIV's

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📋 Eligibility rules (as published)
Inclusion Criteria: * prescribed ART, * willing to sign informed consent (including communication with one's primary HIV provider) Exclusion Criteria: * Relevant drug resistance mutations (per medical record) that compromises activity of Cabotegravir (CBG) + rilpivirine (RPV) * disallowed medications, * pregnancy. * Mental health, cognitive, or behavioral dysfunction that in the opinion of the site PI would impair participation; * severe illness/hospitalization at the time of enrollment, * plan to move away in the next 12 months.
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What it tests

  • The SAVVY intervention includes CHOICE counseling and shared decision-making regarding ART preference (informed by the evidence-based HIV-ASSIST) and facilitating LA-ART access
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Where

1 site
Johns Hopkins University
Baltimore, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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