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โ† Trials
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Validation of the Efficacy of Air Purifiers in Indoor Environment and Allergic Symptoms in Allergic Rhinitis Patients

RecruitingNAAges 19 Years - 60 YearsAllYonsei University
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In plain words

What the trial is, and whether it could suit you

This study targets adult patients between the ages of 19 and 60 who were diagnosed with allergic rhinitis caused by indoor inhalation antigens. Patients with moderate to severe and persistent allergic rhinitis who continue to require medication such as antihistamines and nasal spray steroids for allergic rhinitis are the subjects of this study. Patients who participate in the study will install air purifiers for a certain period of time and observe the objective and subjective improvement of rhinitis symptoms. The study is conducted on two separate occasions for four weeks, and there is a two-week period between the two periods of no use of air purifiers. There are two types of air purifiers: 1)It is an air purifier with a HEPA filter and a VOC filter, and 2) a fake air purifier without air cleaning function. Subjects are divided into Group A and Group B. Group A will receive a fake a

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * adults aged 19 to 60 * A person with moderate-severe persistent allergic rhinitis diagnosed by an allergy specialist or otolaryngologist and maintained without any change in treatment for more than one month * Total nasal symptom Score โ‰ฅ 8 * Patients with allergic rhinitis caused by indoor inhalation antigen antigens (House dust mites ยฑ If the wheal size of the pet skin test is greater than 3mm or the concentration of specific IgE measured by ImmunoCAP โ‰ฅ 0.35 kUA/L) * A person who spends at least 8 hours/day per week in the home where the cleaner will be installed * A person with a wi-fi installed in the home where the purifier will be installed * A person who can read and write in Korean * A person who fully explains the contents, decides to participate in the study according to his/her free will, and signs a written consent form approved by each agency IRB Exclusion Criteria: * Patients sensitized to seasonal antigens (tree, grass or weed pollen) * Rhinitis patients caused by causes other than allergic rhinitis (drug rhinitis, vascular rhinitis, infectious rhinitis, etc.) * Anyone who has required more than 2 weeks of systemic steroid use in the last 3 months * A person taking antihistamines for reasons other than rhinitis (chronic urticaria, etc.) * Those with anatomical abnormalities that cause nasal congestion, such as non-segmental curvature and non-segmental species * A person who has a plan to move during the study period or is scheduled to leave where air purifiers are installed for at least five consecutive days (e.g., travel, business trip, etc.) * A person who has already used an air purifier within the last three months * Pregnant women, lactating women, persons lacking decision-making ability, persons accommodated in facilities * A person whose researcher is deemed unfit to participate in clinical research due to other reasons
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What it tests

  • HEPA + VOC collecting filter purifier
  • fake air purifier
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Where

1 site
Yonsei University
Seoul, South Korea
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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