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Tegoprazan And Lansoprazole Effectiveness in Bleeding Peptic Ulcer Treatment

RecruitingNAAges 18 Years - anyAllMario Steffanus
NCT06894992 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare the effects of tegoprazan vs lansoprazole in healing bleeding peptic ulcers. It will also teach about the safety of both modalities. The main questions it aims to answer are: How does the effectiveness of Tegoprazan compare with Lansoprazole in two weeks of healing rate bleeding peptic ulcer patients in the Indonesian population? Researchers will compare the drug tegoprazan to lansoprazole with a double-blind randomized control to see their effect on healing bleeding peptic ulcers. Participants will: Take drug tegoprazan 50 mg OD or lansoprazole 30 mg OD every day for 2 weeks Endoscopic examination at the beginning before treatment and after completion of treatment within 2 weeks Record of their adverse effect occurrence

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📋 Eligibility rules (as published)
Inclusion Criteria: * Subjects diagnosed with upper gastrointestinal bleeding caused by peptic ulcer through gastroscopic examination Exclusion Criteria: * Allergic to Tegoprazan or Lansoprazole * Diagnosed with gastric or duodenal cancer, pregnant * History of H. pylori infection treatment failure * Presence of comorbidities such as chronic kidney disease or decompensated liver cirrhosis * Alcohol consumption * Undergoing chemotherapy
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What it tests

  • Tegoprazan
  • Lansoprazole
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Where

2 sites
Cipto Mangunkusumo National General Hospital
Jakarta, Indonesia
Atma Jaya Hospital
Jakarta, Indonesia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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